Preparation of Type-specific Antisera to Reoviruses

Preparation of Type-specific Antisera to Reoviruses.

Preparation of type-specific antisera to reoviruses has been handicapped by the ubiquitous distribution of these viruses and frequent occurrence of reovirus antibodies in many species of animals. Antisera prepared in rhesus monkeys at this laboratory have shown extensive crossings between the three types (Table 1). Similar crossreactions have been observed in antisera prepared in rabbits (A. M....

Studies on the Production of Specific Hyperimmune Antisera Against Type A F.M.D. Virus

studies on the production of specific hyperimmune antisera against type a r.m.d. virus

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The Use of Specific "lymphocyte" Antisera to Inhibit Hypersensitive Reactions of the "delayed" Type

Rabbit antisera against normal guinea pig lymph node, when injected into guinea pigs, produced transient depression of the level of blood lymphocytes. It had no effect on other circulating cellular elements. Repeated injection over several days produced lymphopenia, which became progressively less marked with continued treatment, and clear-cut depletion of small lymphocytes in lymph nodes, whet...

Glutamine synthetase from rat liver. Purification, properties, and preparation of specific antisera.

As the initial aspect of investigations on the regulation of glutamine synthetase in rat hepatomas and in hepatoma cell culture systems, glutamine synthetase from rat liver was purified to apparent homogeneity. A single protein band is found in gels after electrophoresis in three separate systems, and a constant enzyme specific activity is found in fractions containing glutamine synthetase acti...